This fragrance tells a royal story, inspired by 800 years of tradition, just waiting to become yours. A regal tribute to the gift of love from Caterina de' Medici to the King of France. Acqua della Regina is the oldest fragrance from the Officina Profumo-Farmaceutica of Santa Maria Novella. Acqua di S.M. Novella – also known as Acqua della Regina – celebrates the perfume that Caterina de' Medici commissioned from the Dominican friars in 1533 and brought with her to France when she married Henry of Valois. Acqua della Regina Eau de Cologne 100 ml is a fresh and citrusy bouquet.