Pycnogenol Creme with Vitamins C, E, and A Only derma e has blended Pycnogenol with vitamins C, E and A into a light moisturizing creme that helps reduce the appearance of fine lines and wrinkles, and assists in rebuilding collagen fibers for improved skin texture and firmness. Daily use will result in smoother, healthier looking skin with the visible signs of aging diminished. Ideal for dry or sensitive skin, for those with Rosacea or skin inflammation, and for those who enjoy a light, silky-smooth rapidly absorbing creme.